Silencing the Double-Stranded RNA Binding Protein DGCR8 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion
نویسندگان
چکیده
منابع مشابه
Silencing of the long non-coding RNA NEAT1 suppresses ovarian cancer cell proliferation, migration and invasion
Increasing evidence reveals that long noncoding RNAs (lncRNAs) are involved in the development of various human cancers including ovarian cancer. LncRNA nuclear enriched abundant transcript 1 (NEAT1) is an essential structural determinant of nuclear body paraspeckles. Although aberrant expression and prognostic value of NEAT1 has been recently reported in various human cancers, NEAT1 was not fu...
متن کاملshRNA-mediated downregulation of α-N-Acetylgalactosaminidase inhibits migration and invasion of cancer cell lines
Objective(s): Extracellular matrix (ECM) is composed of many kinds of glycoproteins containing glycosaminoglycans (GAGs) moiety. The research was conducted based on the N-Acetylgalactosamine (GalNAc) degradation of ECM components by α-N-acetylgalactosaminidase (Nagalase) which facilitates migration and invasion of cancer cells. This study aims to investigate the effects of Naga-shRNA downregula...
متن کاملAuthor's response to reviews Title: Plexin-B1 silencing inhibits ovarian cancer cell migration and invasion Authors:
Shuangmei Ye ([email protected]) Xing Hao ([email protected]) Ting Zhou ([email protected]) Mingfu Wu ([email protected]) Juncheng Wei ([email protected]) Yongjun Wang ([email protected]) Li Zhou ([email protected]) Xuefeng Jiang ([email protected]) Li Ji ([email protected]) Yin Chen ([email protected]) Lanying You ([email protected]) Yiqun Zhang ([email protected]...
متن کاملmiR-506 inhibits cell proliferation and invasion by targeting TET family in colorectal cancer
Objective(s): Ten-eleven translocation (TET) family members have been shown to be involved in the development of many tumors. However, the biological role of the TET family and its mechanism of action in colorectal carcinogenesis and progression remain poorly understood. Materials and Methods:We measured the expression levels of TET family members in colorectal cancer (CRC) specimens, in the c...
متن کاملUp-regulation of Foxp3 inhibits cell proliferation, migration and invasion in epithelial ovarian cancer.
The transcription factor Forkhead Box P3 (Foxp3) has been shown to play important roles in the occurring of regulatory T cells (Tregs). Limited evidence indicated that it was also expressed in tissues other than thymus and spleen, while, very recently, it was identified as a suppressor gene in breast cancer. However, the precise role and molecular mechanism of the action of Foxp3 in ovarian can...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmaceutical Research
سال: 2013
ISSN: 0724-8741,1573-904X
DOI: 10.1007/s11095-013-1219-9